An
edible battery that could power medical devices put inside the body to treat
diseases has been created using the skin pigment melanin. The researchers said
they were able to build a prototype battery that could power a tiny 5 milliWatt
device for 18 hours, which would be enough to gradually release a vaccine or to
sense changes to bacteria in the gut and release medicine in response. Ordinary
batteries, which are much more powerful, are used to power things like
pacemakers but are toxic and have to be insulated from the body.
The
batteries makers are believed to be harmless because they are made out of
natural materials. For decades, people have been envisioning that one day, awe
would have edible electronic devices to diagnose or treat disease. But if you
want to take a device every day, you have to think about toxicity issues. That’s
when we have to think about biologically derived materials that could replace
some of these things you might find in a RadioShack.
The
beauty is that by definition an ingestible, degradable device is in the body
for no longer than 20 hours or so. Even if you have marginal performance, which
we do, that’s all you need. Various different kind of melanin, which is found
in our skin, hair and eyes, absorb ultraviolet light to protect people from its
harmful effects. But they also bind and unbind metallic ions, which is
essentially what happens in a battery. The researchers experimented with
different kinds of batteries using melanin pigments as positive and negative
terminals along with other materials such as copper and iron that are also
found in the body, they reported.
Researchers
found basically that they work. The exact numbers depend on the configuration,
but as an example, we can power a 5 milliWatt device for up to 18 hours using
600 milligrams of active melanin material as a cathode. The researchers are now
working on making edible batteries with pectin – a gelling agent used to make
jam – and other natural materials. They hope to create packaging that could
allow an edible battery to be used in stomach. Researchers envision using the
battery for sensing gut micro biome changes and responding with a release of
medicine, or for delivering bursts of a vaccine over several hours before
degrading.