A simple
blood test that can detect cancer before any symptoms are noticeable has been
developed. The scientists, who unveiled the test at the British science
festival in Swansea, compared the new test to a smoke detector, because it does
not actually find cancer but changes to red blood cells that occur when cancer
is present. Discovering cancer early is a key factor in successful treatment. If
a tumour is caught in a single part of the body, there is a much better chance
that it can be removed surgically, if the cancer has spread to other organs,
the chance the patient will die is much higher. Because it is a simple blood
test, it could be used to monitor people with a high risk of getting the
disease. The test can be likened to a ‘cancer smoke detector’ because a smoke
detector does not detect the presence of fire in our homes but it’s by-products
– smoke…. This test detects cancer, by detecting the ‘smoke’ – mutated blood
cells.
The researchers said the test could detect
cancer before there are any noticeable symptoms. The researchers worked on
developing the test over the past four years, studying 300 healthy people,
patients with signs of pre-cancer and patients with the oesophageal form of the
disease. The test detects mutations in proteins on the surface of red blood cells.
In healthy people, the number of mutations of this type averages about five per
million, but in cancer patients there can be 50 to 100 mutants per million. These
mutations do not have a role in the development of cancer, with the researchers
describing the effect as “collateral damage” caused by the disease. Asked how
significant the test would be if it worked for all cancers, researcher said: “With
any cancer, if it is caught early enough and surgically removed, that is the
biggest impact on the outcome of a cancer diagnosis.