This might be the ultimate
do-it-yourself project: Doctors are testing a device that would let women do
part of their own breast reconstruction at home. It’s aimed at not only making
treatment for breast cancer more comfortable and convenient, but also giving
women a sense of control – something cancer often takes away. According to a
recent study published in ‘The Lancet’, India and China have the largest number
of women with breast and cervical cancer. Many patients of breast cancer
undergo surgery to remove a cancerous breast, and several choose reconstruction
with an implant. To make room for a permanent one, many patients get a tissue
expander, a temporary pouch that is gradually enlarged with saline to stretch
the remaining skin and muscle. This means trips to the doctor every week or two
for several months for injections of saline into the pouch, which can be
painful. This device is called AeroForm. AeroForm patients finished tissue
expansion in half the time and were able to get implants a month sooner than
others who had the usual saline treatments. There was no difference in rated of
side-effects such as infections, but seven air expanders malfunctioned versus
only one saline one. The device was tweaked to fix the problem.
Monday, 21 November 2016
Pig's Heart Beats In Monkey's For 51 Days
The prospect of humans being given
transplanted hearts from other animals appeared to be a step closer after South
Korean scientists reported they had successfully installed a pig’s heart in a
monkey. Researchers at National Institute of Animal Science (NIAS) said the
heart had been genetically modified to reduce the risk of being rejected by the
crab-eating macaque. It was still alive some 51 days after the procedure when
the researchers reported their results, breaking the previous record of 43
days, according to a report by the Yonhap news agency. The monkey was also
given a cornea from the pig’s eye. The pig, called Mideumi, was genetically
engineered in 2010 to produce an excessive amount of a membrane protein that
helps reduce the risk of the organ being rejected after transplantation. Currently
transplant patients have to take immune-suppressing drugs to stop their natural
defense mechanisms from attacking the foreign body. Finding a way to avoid this
response would be a major breakthrough. NIAS said it also planned to work with
a bioengineering firm to transplant pancreatic tissue from pigs to monkey in an
effort to find new ways to treat diabetes. Pigs’ hearts, seen as a close match
to the human version have also been transplanted into other animals. One was
kept healthy and beating inside the abdomen of a baboon for nearly three years.
The baboon still had its original heart and did not need the pig’s one, but the
fact it was able to survive for so long without being destroyed by its immune
system was a significant accomplishment for the researchers. Muhammad
Mohiuddin, a cardiac transplant surgeon at National Heart, Lung, and Blood
Institute in Bethesda, US, who lead the baboon study, told Science magazine: “People
used to thick that this was just some wild experiment and it has no
implications. I think now we’re all learning that xenotransplatation in humans
can actually happen.”
Self-Driving Cars Set For Real Test In Seoul
Self-driving cars will soon hit the
road in South Korea as the country seeks to overtake other nations that have
sped ahead with automated driving technology. Seoul National University
professor Seo Seung-woo says a self-driving car develop by this team will start
roaming Seoul streets early next year, thanks to a revised law that took effect
on 15 November. His team has been testing automated driving inside the
university’s campus with a sedan outfitted with sensors and cameras. The vehicle
drove more than 10,000 kilometres in the past two years without incident, but
could not leave the campus because of regulations. The new law allows automated
cars to travel on public roads around the country. Eight self-driving cars,
including those of Seo’s team, are registered with the country’s transport
ministry and have been tested in limited conditions. Seo unveiled two upgraded
vehicles that can navigate narrow streets and identify road signs and traffic
lights. One will be tested in traffic after it is certified by the government.
South Korea has been slow to introduce driverless cars on public roads while
other countries have been testing automated driving for public transport, such
as taxis and buses, in real traffic conditions.
Smell Test Gauges Alzheimer's Risk
Researchers have developed a new
non-invasive method to identify people at the risk of developing Alzheimer’s
disease on the basis of their ability to recognize and recall odors. The protocol
testing the ability to recognize, remember and distinguish between odors was
able to identify older individuals who – according to genetic, imaging and more
detailed memory tests – were at increased risk of Alzheimer’s disease. There is
increasing evidence that the neurodegeneration behind Alzheimer’s disease
starts at least 10 years before the onset of memory symptoms. The development
of a digitally enabled, affordable, accessible and non-invasive means to
identify healthy individuals at risk is a critical step to developing therapies
that slow down or halt Alzheimer’s disease progression. The battery of four
tests developed by the MGH team addresses both olfactory and cognitive
functions – and involves participants being presented with different smells for
two seconds each, and then asked to choose from a group of words, one that best
describes each odour. The study recruited 183 participants, most of who were
enrolled in ongoing studies at the MGH-based Massachusetts Alzheimer’s Disease
Research Centre.
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