Scientists have identified a
compound that may delay the aging processes and prevent Alzheimer’s and
Parkinson’s diseases. As we live longer and longer, a lot of people are
occupied with their state of health and, not least, quality of life in old age.
However, none of the existing explanations are able to explain all the
biological aspects of human aging. Previous research has shown that a main
process in aging is the capacity of the cells to keep our genes, our DNA, more
of less intact. However, changes in the cells’ power stations, the
mitochondria, also affect aging processes. Researchers from the University of
Copenhagen and the National Institute of Health in the US have shown that the
coenzyme NAD+ bridges the gap between two main aging theories – repairs to the
DNA and poor functioning mitochondria. This study shows an age dependent
decrease in the level of NAD+, and this decrease is far greater for organisms
with early aging and a lack of DNA repairs. Adding NAD+ postponed both the
aging processes of the cells and extended life in worms and in a mouse model. The
researchers bred mice and roundworm with the illness Ataxia telangiectasia
(A-T) for the purpose of the study. In A-T patients, the part of the brain that
is responsible for coordination gradually degenerates, DNA repairs are lacking,
and they experience other symptoms characteristic of early aging. This new
study stresses that NAD+ plays a main role both in maintaining the health of
the mitochondria and in their capacity for repairing the genes.
Tuesday, 1 November 2016
Docs Separate Twins Joined At The Head In 20-Hour Operation
Forty medical experts at a New York
hospital on 14 October successfully separated conjoined twins attached at the
head after a 20 hour procedure. Officials at Montefiore Medical Centre in the Bronx
said the 13 month old boys, Jadon and Anias McDonald, were recovering from the
marathon surgery. Their mother Nicole McDonald said the atmosphere at the
hospital was one of celebration mixed with uncertainty. She said Jadon did
better than Anias during the procedure, adding that doctors predicted the
former might not be able to move part of his body at first. The operation was
led by pediatric neurosurgeon Dr. Oren Tepper. In 2004, Goodrich also
successfully separated Carl and Clarence Aguirre and a half dozen other sets of
twins from around the world.
1st Drone Delivery Service For Blood
Rwanda has launched a national
level delivery program that will allow blood and plasma to be flown to health clinics
across the country by drones. It’s considered the world’s first commercial
delivery service using drones. The poor road conditions have often delayed
delivery of medical supplies to the rural western part of the county by hours
and sometimes even days. Recode.net reports that the program has been launched
in collaboration with California based drone startup Zipline, shipping company
UPS Foundation and Gavi, a vaccine fund backed by Bill Gates. The Rwandan
government is paying for the service, which costs about the same as the
motorbike blood deliveries the country relies on today. Zipline itself is a
private company that includes among its investors Microsoft co-founder Paul
Alien and Yahoo founder Jerry Yang. CNN
Money reported that earlier it took an average of four hours to make an
emergency delivery to a hospital. With a drone, those can be completed in 15
minutes, according to Jean Philbert Nsengimana, Rwanda’s minister of
information and communication technology. In certain cases it was really bad. Roads
could become impassable during the rainy season, slowing vital deliveries from
the National Centre for Blood Transfusion.
Soon, Google Maps For The Body
Scientists launched a global
initiative on 14 October to map out and describe every cell in the human body
in a vast atlas that could transform researchers understanding of human
development and disease. The atlas, which is likely to take more than a decade
to complete, aims to chart the types and properties of all human cells across
all tissues and organs and build a reference map of the healthy human body. Cells
are fundamental to understanding the biology of all health and disease, but
scientists cannot yet say how many we have, how many different types there are,
or how they differ from one organ to another. The human cell atlas initiative
is the beginning of a new era of cellular understanding. Researchers will
discover new cell types, find how cells change across time during development
and disease, and gain a better understanding of biology. The project is
currently led by a team from the Broad Institute of the Massachusetts Institute
of Technology (MIT) and Harvard in the United States, the Sanger Institute and
Wellcome Trust in Britain. The plan is for research teams and funder worldwide
to collaborate. By making the atlas – essentially a vast database of cellular
detail – freely available to scientists the world over, the scientists hope to
transform research into human development and the progression of diseases such
as asthma, Alzheimer’s and cancer. The human body is made of trillions of cells
– the fundamental units of life – which divide, grow and take on distinct
functions in embryo, eventually leading to different cell types such as skin
cells, neutrons or fat cells. Until recently, scientific knowledge of cells has
been limited to what can be found out by looking at them under microscopes, or
by genetically analyzing clumps of hundreds or thousands of cells and finding
their average properties. But technological advances in field known as single
cell genomics means researchers can now separate individual cells from
different tissues and organs, analyze their properties and measure and describe
which molecules are produced in each.
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