Scientists
have developed a new 3D-printing process that uses strands of cow cartilage as
bioink, an innovation that may help create tissue patches for worn-out joints
in arthritis patients. Cartilage is a good tissue to target for scale-up
bioprinting because it is made up of only one cell type and has no blood
vessels within the tissue. The tissue cannot repair itself.
Previous
attempts at growing cartilage began with cells embedded in a hydrogel – a substance
composed of polymer chains and about 90% water – that is used as a scaffold to
grow the tissue. “Hydrogels don’t allow cells to grow as normally,” said
Ibrahim T Ozbolat, associate professor at Pennsylvania State University, US.
This leads
to tissues that do not have sufficient mechanical integrity. The cartilage
produced under the new experiment is very similar to native cow cartilage. The mechanical
properties are inferior, but better than the one with hydrogel scaffolding.
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