Scientists
are now contemplating the fabrication of a human genome, meaning they would use
chemicals to manufacture all the DNA contained in human chromosomes. The prospect
is spurring both intrigue and concern in the life science community because it
might be possible, through cloning, to use a synthetic genome to create human
beings without biological parents. The project is still in the idea phase.
The project
could have a big scientific payoff and would be a follow-up to the original
Human Genome Project, which was aimed at reading the sequence of the three
billion chemical letters in the DNA blueprint of human life. The new project
would involve not reading, but rather writing the human genome – synthesizing all
three billion units from chemicals.
The project
was not aimed to creating people, just cells, and would not be restricted to
human genomes. Rather it would aim to improve the ability to synthesize DNA in
general, which could be applied to various animals, plants and microbes.
Scientists and companies can now change the DNA in cells, for example, by
adding foreign genes or changing the letters in the existing genes. This technique
is routinely used to make drugs, such as insulin for diabetes, inside
genetically modified cells, as well as to make genetically modified crops. But
synthesizing a gene, or an entire genome, would provide the opportunity to make
even more extensive changes in DNA.
No comments:
Post a Comment