Scientists
have succeeded in altering the patterns on a butterfly’s wings by tweaking just
one or two genes, an advance that may help understand how color patterns and shapes
evolved in the insects. By using the new method of CRISPR, a gene editing tool,
and produced a butterfly lacking the large round markings known as eyespots. In
another experiments also produced changes in other parts of the wing. The distal-less
gene, in particular, unveiled itself as a jack of all trades gene that plays
roles in shaping several parts of the body. Deleting it not only caused the
butterfly to have extra eyespots, but to have shorter legs and antennae. It takes
dozens or hundreds of genes to make an eyespot, so it was remarkable to find
that only one or two genes are required to add or subtract these complex
patterns.
Sunday, 4 September 2016
Living Bone Grown in Lab to Boost Cure For Facial Defects
In a
first, scientists have grown a living bone in the lab to repair large defect in
the head and face of patient, taking a step forward in improving treatments for
people with craniofacial defects. A new technique developed, uses autologous
stem cells derived from a small sample of the recipient’s far and replicates
the original anatomical structures of the bone. The researchers have been able
to show, in a clinical-size porcine model of jaw repair, that this bone, grown
in vitro and then implanted, can seamlessly regenerate a large defect while
providing mechanical function. The quality of the regenerated tissue, including
vascularisation with blood perfusion, exceeds what has been achieved using
other approaches. Researchers fabricated a scaffold and bioreactor chamber
based on images of the jaw defect, to provide and anatomical fit. The scaffold
they built enabled bone formation without the use of growth factors, and also
provided mechanical function. They then isolated the recipient’s own stem cells
form a small fat aspirate and, in just three weeks, formed the bone within a
scaffold made from bone matrix, in a custom-designed per-fused bioreactor.
Gravitational Waves Detected For 2nd Time By The Collision Of Two Black Holes
For the
second time, scientists have detected gravitational waves created by the collision
of two black holes 1.4 billion light years away, which once again confirms
Einstein’s theory of general relativity. The scientists detected the
gravitational waves – ripples through the fabric of the space-time continuum –
using the twin Laser Interferometer Gravitational-wave Observatory (LIGO)
interferometer in the US.
On December
26 last year, both detectors situated more 3,000 kilometer apart, picked up a
very faint signal amid the surrounding noise. While LIGO’s first detection,
reported on February 11 this year, produced a clear peak in the data, this
second signal was far subtler, generating a shallower waveform that was almost
buried in data. The researchers calculated that the gravitational wave arose
from the collision of two black holes, 14.2 and 7.5 times the mass of the Sun.
The signal
picked up by LIGO’s detector encompasses the final moments before the black holes
merged. In the final second, while the signal was detectable, the black holes
spun around each other 55 times, approaching half the speed of light, before
merging in a collision releasing a huge amount of energy in the form of
gravitational waves, equivalent to the mass of the Sun. This cataclysm, occurring
1.4 billion light years away, produced a more massive spinning black hole about
20.8 times the mass of the Sun. This second detection of gravitational waves
also successfully tested LIGO’s ability to detect incredibly subtle
gravitational signals.
LIGO’s
two interferometers, each four kilometres, are designed in such a way that each
detector stretches by an infinitesimal amount if a gravitational wave were to
pass through. On September 14 last year, the detectors picked up the very first
signal of a gravitational wave, which stretched each detector by as little as a
fraction of a proton’s diameter. Just four months later, LIGO recorded a second
signal, which stretched the detectors by an even smaller amount. In its first
four months, the advanced LIGO detectors have already detected two signals of
gravitational waves, produced by the collision of two very different binary
black hole systems.
To Combat Global Warming, Carbon Dioxide is Turned Into Stone
Scientists
have found a quick way – but not a cheap one – to turn heat-trapping carbon
dioxide gas into harmless rock. Experts say the results of a two-year, $10
million experiment called CarbFix, conducted about 540m deep in the rocks of
Iceland, offer new hope for an effective weapon to help fight man-made global
warming. When an international team of scientists pumped a carbon dioxide and water
mix into underground basalt rocks, basic chemistry took over. The acidic
mixture dissolved the rocks’ calcium magnesium and formed limestone, a
permanent natural jail for the heat-trapping gas.
Scientists,
who had done this before in the lab, thought the process could take thousands
or even hundreds of years. But after just two years, 95% of the gas, was
captured and converted. One of the methods to battle climate change, in
addition to reducing fossil fuel emissions, is to capture carbon dioxide from
the air or powerplants. Carbon capture is not the silver bullet, but it can
contribute significantly to reducing carbon dioxide emissions.
Carbon capture
however can be expensive – especially the capturing part. Once the gas is
grabbed from the air, storage is another issue. It can be stored underground, injected
in depleted oil wells, but there are concerns about monitoring it and
preventing it from escaping. Injecting it into basalt and letting nature take
its course can solve that problem. But at $17 per tonne of carbon dioxide, it
can cost a couple times more than injecting it into old wells. There’s basalt
all over the world, in places like the Pacific Northwest, India and South
America. But even more promising is the ocean floor, which is full of basalt and
a good place to store the carbon dioxide.
Saturday, 3 September 2016
Astrophysicists Discover Canarias Einstein Ring in Space
On 16
May 2016, an international team of astrophysicists discovered a new optical Einstein ring called
Canarias Einstein Ring. Einstein Ring is a distorted image of a galaxy, the
source, which is very distant from the Earth. The results of the discovery were
published in the international journal Monthly Notices of the Royal
Astronomical Society. The discovery was made by a team comprising of doctoral
student Margherita Bettinelli from the Instituto de Astrofisica de Canarias
(IAC) and the University of La Laguna (ULL) of Spain. The rare phenomenon was
discovered in the Sculptor constellation, IAC J010127-334319, in the vicinity
of the Sculptor Dwarf Spheroidal Galaxy
New Material Makes N-Fuel Recycling Cleaner, Cheaper
Scientists
have found a new material that may help recycle and reduce wastage of nuclear
fuels as well as save energy, making the reprocessing of radioactive materials
cleaner and less expensive. Conventional technologies to remove these
radioactive gases operate at extremely low, energy-intensive temperatures. By
working at ambient temperature, the new material – known as metal-organic
frameworks – can save energy, make reprocessing cleaner and less expensive. The
reclaimed materials can also be reused commercially.
A New DNA Treatment As The Future Of Cancer Treatment
A revolutionary
new DNA treatment technique makes you six times more likely to beat cancer. The
new technique involves having a simple £200(Rs 19,386) DNA test of your tumour
first. This them tells doctors precisely which drugs or therapies are most
suited to you, rather than relying on the standard treatment.
Precision
medicine studies presented at the American Society of Clinical Oncology annual
meeting are expected to show unprecedented results. One study of 13,000
patients taking part in early clinical trials of drugs found those undergoing
genetic testing of their tumours before any treatment – so that they could then
be given targeted therapies instead of standard drugs were six times more
likely to see their tumours shrink or disappear altogether. It is the first analysis
of precision medicine treatments.
It is a
very different way to treatment. It’s the most exciting thing since
chemotherapy. It was about using reliable technology to better treat patients and
giving them the most appropriate choice. Precision medicine was about finding
the right key for the lock, finding out what it is that is driving the tumour,
what make it tick. At the moment, it is informed guesswork, so that treatment
often doesn’t work for large numbers of patients. I believe the potential of
precision medicine is huge.
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