A single dose of a new
bioengineered gel may deliver a full course of antibiotic therapy for middle
ear infections, making treatment for this common childhood illness much easier
and potentially safer. Middle-ear infection, or otitis media, is the number one
reason for pediatric antibiotic prescriptions, but getting oral antibiotics
into young children several times a day for seven to 10days is a daunting task.
With oral antibiotics, you have to treat the entire body repeatedly just to get
to the middle ear. With the gel, a pediatrician could administer the entire
antibiotic course all at once, and only where it’s needed. Squirted into the
ear canal, the gel quickly hardens and stays in place, gradually dispensing
antibiotic across the eardrum into the middle ear.
Friday, 30 September 2016
Lab-Grown 3D Lungs to Help Study Diseases
Scientists, including those of Indian
origin, have successfully grown 3D lungs in the lab, using stem cells, which
can be used to study diseases that are difficult to understand with
conventional methods. By coating tiny gel beads with lung-derived stem cells
and then allowing them to self-assemble into the shapes of the air sacs found
in human lungs, researchers created 3D “organoids”. The laboratory-grown tissue
can be used to study diseases including idiopathic pulmonary fibrosis, which
has been difficult to study using conventional methods.
While researchers haven’t built a
fully functional lung, they’ve been able to take lung cells and place them in the
correct geometrical spacing and pattern to mimic a human lung. Idiopathic
pulmonary fibrosis is a chronic lung disease characterized by scarring of the
lungs. The scarring makes the lungs thick and stiff, which over time results in
progressively worsening shortness of breath and lack of oxygen to the brain and
vital organs.
Finally, Tech to Boost Old Drugs With Hydrogen is Here
Drug makers are breathing new life
into old drugs – with hydrogen. Substituting a heavier form of the gaseous
element in drugs can slow their breakdown by the body, leaving them in the
bloodstream longer. That means a patient can take them less frequently – and that,
in theory, might reduce the severity of side effects. While the technology has
been around for 40 years, it’s taken that long to understand it well enough to
bring such a treatment before the US Food and Drug Administration. The
regulator is reviewing that would be the first medicine made with deuterium, or
heavy hydrogen.
This is new concept, and FDA approval will
make it a lot clearer for the field. Deuterium provides unique properties that
cannot be attained in any other way. The approach interferes with one of the
ways that the body metabolizes or eliminates drugs, involving enzymes that “nibble
away” at the hydrogen in the molecule. Deuterium is essentially armored
hydrogen, tougher and more difficult for the enzymes to break down, so it
sticks around longer in the body. Other than that, the drug works the same as
the original.
Wednesday, 28 September 2016
Now, Just Spray And Make Cup of Tea
If there is one thing the British
enjoy, it is a good cup of tea and one English drinks maker has come up with an
unusual way of making the brew – sprayed into a cup form an aerosol can. No More
Tea Bags is prebrewed and dispensed from an aluminum spray can. Drinkers squirt
a small amount of the concentrated tea into a cup, and add hot water and milk
if desired. It was really about just trying to make a better cup of tea. Of course
there’s an element of convenience with this and not having a soggy tea bag to
get rid of tat the end of it. Developer uses wine making equipment to make the
equivalent of a giant pot of tea to produce the spray, one can of which yields
about 20 cups of average strength tea.
Developer starts developing it in
glass. The trouble was he had to use chemical preservatives and he didn’t want
to do that. He realized that he could put the tea in (an aerosol can) in a
sterile condition and it’s completely isolated from the atmosphere. Launched in
august in a small number of independent shop, No More Tea Bags come in three
flavours: English breakfast, Earl Grey and Jasmine. This is probably more like your
average cup of tea. There’ll be a lot of people who’d probably love this
flavour and this convenience.
Food Waste May Store Solar, Wind Energy
Sugar alcohols – an abundant waste
product of the food industry – mixed with carbon nanotubes could be used to
store excess solar and wind energy for times when the Sun is down or the air is
still, scientists have found. The researchers wanted to study how mixing carbon
nanotubes with sugar alcohols might affect their energy storage properties. The
new insights could assist in the future design of sugar alcohol-based energy
storage systems
China Launches Second Space Station Tiangong 2
China has launched its second space
station in a sign of the growing sophistication of its military backed
programme. The Tiangong 2 was carried into space on 15 September night atop a
Long March 7 rocket from the Jiuquan Satellite Launch Centre on the Edge of the
Gobi Desert in northern China. Plans call for the launch next month of the
Shenzhou 11 spaceship with two astronauts on board to dock with the station and
remain on board for a month. The station, whose name means “Heavenly Palace,”
is considered a stepping stone to a mission to Mars by the end of the decade.
Boeing Altering Planes to Help Passenger Beat Jet Lag
During the development of the 787 Dreamliner,
Boeing encountered countered countless engineering hurdles. One of which was
the decision to build much of the plane out of carbon fiber reinforced plastics
and other composite materials instead of aluminum most, commonly used on
airliners. While the engineering of the composite airframe may have been a
challenge, it’s a decision that allowed Boeing to make a major change to its aircraft
that could greatly reduce the effect of jet lag on its passengers. The Dreamliner
has a composite fuselage and that allowed them to pressurize it at whatever
altitude they wanted because the material is not as susceptible to fatigue.
The very symptoms they attribute to
jet lag may actually be attributed to acute mountain sickness, which affects
individuals exposed to altitudes above 6,500 feet. A study with the help of
Boeing found that flyers that go from sea level up to 8,000 feet saw the oxygen
content in their blood fall 4%. The research showed passengers’ bodies reacted
at 6,000 feet similar to that at sea level. So they decided to pressurize the
Dreamliner at 6,000 feet. At 6,000 feet, the cabin air is denser and has a
greater level of oxygen saturation. As result, the body does not have to work
as hard to oxygenate blood and sustain itself. Boeing has also increased in
cabin humidity as well as hot a new air-filtration system to reduce jet lag.
Boeing upcoming 777X wide body mini jumbo jet, which comes into service in
2019m will also be pressurized at 6,000 feet.
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